A retrospective, pathology-based cohort study published in BMC Women’s Health evaluated hysterectomy specimens from a tertiary center between 2012 and 2017. Among 2,028 hysterectomies, 297 patients had histologically confirmed adenomyosis, giving a prevalence of 14.6%. Of these, 119 (40.1%) had adenomyosis without coexisting leiomyoma or endometriosis, while 178 (59.9%) had adenomyosis with coexisting leiomyoma and/or endometriosis. Patients without coexisting disease were older than those with coexisting disease (54.2 vs 50.0 years).

Menorrhagia was less frequent (50 vs 115 patients), whereas postmenopausal bleeding (24 vs 19) and uterine prolapse (17 vs 12) were more frequent. Concurrent gynecologic malignancy occurred in 42 patients (35.3%) with adenomyosis without coexisting disease compared with 17 (9.6%) with coexisting disease. Multivariable analysis showed an adjusted odds ratio…