The concept of adjuvant chemotherapy has increased the survival rate of colon cancer stage III patient. Researchers at Standford University have identified Caudal-type Homeobox Transcription Factor 2 (CDX2) as a candidate biomarker of mature colon epithelial tissues and negative CDX2 in stage II and III colon cancer is benefited with adjuvant chemotherapy. Colon cancer is characterized by uncontrolled cell growth in the colon. Most colon cancers originate from small, noncancerous (benign) tumors called adenomatous polyps that form on the inner walls of the large intestine.
These polyps may grow into malignant colon cancers over time if they are not removed during colonoscopy. It is the most common form of cancer especially in developed countries like USA and Japan. Common triggering factor for Colon cancer: Polyps: Presence of pre-cancerous polyps in the large intestine are the most…