Diabetes mellitus (DM) and atrial fibrillation (AF) are associated with increased cardiovascular (CV) and cerebrovascular mortality. 1 Experimental and clinical evidence has suggested that DM is an independent risk factor for AF. It is associated with increased symptom burden, hospitalization, mortality rates, and lower quality of life in AF patients.
1,2 Efforts in developing novel mechanism-based approaches to reduce the AF burden of diabetes patients will be invaluable. 3