The four-year-old boy bought with a fever sore throat for the last four days. He was on oral antibiotics. As local doctor noticed this patch in the throat he was referred here. See figure 1 Second child, the older one is 7 years. Both of them un-immunized . No vaccine taken so far. Many kids in the neighbourhood also.

At the time of admission, the child was sick, drooling of saliva and cervical lymph node enlarged odema neck plus. In view of an unimmunised child, developing this typical patch in the throat provisional diagnosis of diphtheria was made. Took a throat swab for gram stain, and culture and patient were put on Crystalline penicillin,  Diphtheria antitoxin 80000 unit was planned. While administration rashes and BP fall occurred. Under cover of Adrenalin and supportive measures could give 100000 units of antitoxin. Differential diagnosis To rule out other possibilities like…