Cystic Fibrosis (CF) is a serious autosomal recessive genetic disease caused by mutations in the CFTR gene . A child develops CF only if they inherit one defective gene from each parent. Carriers with a single copy of the CF gene do not develop the disease but can pass it on. Because the CF gene is located on autosomal (non-sex) chromosomes, it affects both boys and girls equally. These mutations disrupt the production or functioning of the CFTR protein, which is vital for cells in the lungs and other organs .
This results in thick, sticky mucus that compromises lung function and other body systems. A major complication in CF is chronic lung infection with Pseudomonas aeruginosa —once acquired, it persists lifelong, worsening disease progression. While the burden is immense, ongoing research continues to offer hope. Clinicians depend on young researchers whose efforts may one day unlock…