Synopsis Weight loss is common in patients with chronic heart failure (CHF) and is associated with adverse outcomes like cachexia. The effect of sympathetic antagonism on weight change in patients with CHF is not well defined. Thus, the primary purpose of this study was to evaluate the effect of beta-adrenergic blockade on weight changes in CHF patients. This week’s “MED FACT” discusses a clinical trial from International Journal of Cardiology, “ Effect of beta-adrenergic blockade on weight changes in patients with chronic heart failure ”.

Authors: Shirley Sze, Pierpaolo Pellicori, Syed Kamzi, Alexandru Anton, Andrew L.Clark Key Takeaways: Patients who received beta-blocker were less likely to develop cachexia and more likely to have significant weight gain. Objective: To evaluate the effect of Beta-Adrenergic blockade on weight changes in CHF patients. Study Type: Randomized trial…