Highlights There is a rise in the incidence of obscure gastrointestinal bleeding associated with the use of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs). Misoprostol is effective for the treatment of small bowel ulcers and erosions in patients using low-dose aspirin and NSAIDs. This week's ' JOURNAL WATCH discusses a clinical trial from The Lancet Gastroenterology & Hepatology, “ Misoprostol for small bowel ulcers in patients with obscure bleeding taking aspirin and non-steroidal anti-inflammatory drugs (MASTERS): a randomised, double-blind, placebo-controlled, phase 3 trial ”.
July 2018. Authors : Taha AS; McCloskey C; McSkimming P; McConnachie A. Objective Study Type Participants To assess the efficacy and safety of misoprostol for the treatment of small bowel ulcers and erosions in patients taking low-dose aspirin or NSAIDs Randomized, double-blind,…
