Despite decades of global emphasis on rational prescribing, inappropriate medication use remains entrenched, with the WHO estimating that more than half of all medicines worldwide may still be prescribed or used incorrectly. This gap between guideline recommendations and real-world practice contributes to avoidable ADRs, higher hospitalization rates, and a growing economic burden on patients. LMICs on the Frontline The problem is particularly pressing in low- and middle-income countries, where antimicrobial resistance continues to accelerate amid unwarranted antibiotic use.
An Indian study highlighted practical solutions recommended by clinicians, including administrative directives and targeted online training to help bridge the gap between knowledge and practice. When Guidelines Meet Reality: The Persistent Gap in Rational Prescribing Prescribing errors continue to challenge even…
