Hearing loss is a common sensory defect, with genetic factors being implicated in over 80% of the inherited form. A study recently investigated the role of the MINAR2 gene in sensorineural hearing loss (HL). ## Reference: ## Bademci G, Lachgar-Ruiz M, Deokar M, Zafeer MF, Abad C, Yildirim Baylan M, Ingham NJ, Chen J, Sineni CJ, Vadgama N, Karakikes I, Guo S, Duman D, Singh N, Harlalka G, Jain SP, Chioza BA, Walz K, Steel KP, Nasir J, Tekin M. Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.
Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204084119. ## Do you think genetic approaches targeting MINAR2 can cure hearing loss?
