Cyproheptadine is commonly used as Appetite Stimulant in children. Some statements I came across related to this are: "Adverse effects very common with cyproheptadine and noticed in 30% of patients"- Rodriguez et al J Pediatrics 2013 "CNS adverse effects include drowsiness, irritability, and behavioral changes"- Rodriguez et al J Pediatrics 2013 "When used in children with epilepsy, it decreases seizure threshold, increases the severity of seizures and decreases the efficacy of anti-epileptic medications"- Singh & Goel Fundam Clin Pharmacol 2010. "A popular pharma company has deleted appetite stimulation as an indication for Cyproheptadine, internationally"- Lexchin Can Fam Phy1994.

"Reduces the secretion of ACTH, cortisol, prolactin, and growth hormone"-  von Mühlendahl and Krienke, Monatsschr Kinderheilkd.1978. “Cyproheptadine is an agent with considerable side effects, and it should…