Sarcoma right breast 21 years girl operated 3 times at different places diagnosed as fibroadenoma Histopathology of patient Poorly differentiated carcinoma with papillary and metaplastic features, histologic grade, (tubule formation: 3; nuclear pleomorphism: 3; mitotic index: 3; Total score= 9) No in situ component, perineural invasion, or lymphovascular invasion is identified An immuno-histochemical work up is recommended to characterize the sarcomatous component, in addition to the hormone receptors and HER2/neu. Breast Sarcomas Diagnosis Breast sarcomas are a very rare less than 1% of all breast cancers. Most breast cancer arise in milk ducts, but sarcomas begin in the connective tissue of the breast. Breast sarcomas may be primary or secondary.
Some are inherited genetic disorders causing a primary breast sarcoma. The reason is often unknown. Secondary may occur after radiation…
