ย Click here to participate in the live audience poll 1 ย Click here to participate in the live audience poll 2 ย Click here to participate in the live audience poll 3 ย Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity worldwide, occurring in 5% of all deliveries. 1 PPH is managed using uterotonic agents, transfusion, and nonsurgical and/or surgical interventions. Despite the availability of various management options, the number of PPH-associated deaths and complications remains high.
2 ย ## History of rFVIIa ## Recombinant activated factor VII (rFVIIa) was first designed to treat incidents of bleeding in individuals with congenital hemophilia and inhibitors. The tale began in the 1970s when FVIIa was recognized as one of the activated coagulation factors with the lowest potential for triggering thromboembolic adverse effects. Over the last 30 years,โฆ