Are you being presented with increasing number of patients with vitamin D deficiency? Are your patients showing resistance to vitamin D? What does deficiency and resistance of vitamin D manifests? This article will provide brief information regarding vitamin D deficiency and resistance. Vitamin D is one of the most essential compounds, which is critical for development and physiology in all.

Vitamin D has variety of interactions and activities with calcium, phosphate and bone metabolism. One of the most important biological action is to promote enterocyte differentiation and intestinal absorption of calcium and phosphate. Thus, it helps in maintaining the supply of these two key ions to the rest of the body. Vitamin D deficiency can result in hypocalcemia and hypophosphatemia. Hypocalcemia is often masked by the release of parathyroid hormone (PTH) which is triggered by hypocalcemia…