Case presentation A 59-year-old man presented with respiratory exacerbations causing respiratory failure. He had a significant medical history of COPD. Arterial blood gas examination: pH: 7.26 PaO 2 : 6.7 kPa (10-13.1 kPa) PaCO 2 : 8.9 kPa (4.9-6.1 kPa) HCO 3 : 26 mmol/L (22-28 mmol/L) How will you manage this patient?

*This case is from the Editorial Team of Docplexus and is meant for educational purposes only.