Solve exciting clinical cases specific to your field of interest via Docplexus’ Clinical Case Challenge. Join your fellow doctors to discuss and answer today’s challenge! Case presentation A 48-year-old male reported to the emergency department with swelling and skin lesions on the left lower limb. He developed these symptoms one day ago after receiving a benzathine penicillin injection (1200000 IU) on the left buttock for fever and signs and symptoms of an upper respiratory infection.

The left lower extremity became pale and mottled about half an hour after receiving the injection, followed by edema and coldness. The left leg was tender to touch, and the patient could not bear weight on the same side. Clinical examination Mottled, dark purplish livedoid patches were seen on the buttock, gluteal region, and upper part of the left thigh. Hemorrhagic bullae and skin necrosis were…