This case report is an illustration of the Bruton’s Disease, which encloses details of patient records, from family history to the laboratory findings. The data is mentioned in the lucid format to cover the details of treatment modalities employed while a treating a pediatric patient showing signs of Bruton’s disease. Case: A seven-year-old boy was referred with fever, coughing, and fatigue. He had received Ampicillin-Sulbactam and clarithromycin with the diagnosis of pneumonia and acute otitis media for three days at a local hospital.

History: It was learned that he had previously been hospitalized for pneumonia for five times, had bilateral otitis media which was treatment-resistant for the last two years and had been suffering from upper air way infection 8 - 10 times per year. The first hospitalization for pneumonia was at the age of 15-month-old. He was the first child of…