A new protocol known as enhanced recovery after surgery (ERAS) advocate the use of multimodal analgesia along with the focus on early mobilization and resumption of oral intake. According to the report, this protocol reduced care time by 30% and postsurgical complications up to 50%. Arctic Surgical Group in Anchorage headed by Dr. James price has developed a comprehensive multimodal analgesia protocol in perioperative settings.
The team first used anti-inflammatory drugs such as cyclooxygenase (COX)-1 and COX-2 inhibitor non-steroidal anti-inflammatories (NSAIDS) to block spinal and peripheral COX enzymes. Acetaminophen and corticosteroids are also added to this regime. Further, the regime includes the use of methadone, ketamine, and anticonvulsants such as gabapentin and pregabalin. Lastly, alpha-2 adrenergic receptor agonists, such as clonidine and detomidine were used to produce…
