Autoimmune encephalitis is a group of encephalitis syndromes that cause altered mentality, memory decline, or seizures in association with the presence of serum and cerebrospinal fluid autoantibodies. Early diagnosis is indispensable for early and efficient treatment. This article outlines the advanced laboratory techniques used for the diagnosis of autoimmune encephalitis.

Autoimmune encephalitis (AE) is a group of syndromes that occur in association with autoantibodies which are presumed to be responsible for the development of epilepsy and encephalitis. Patients with AE present a variety of autoimmune disorders that involve B-cell-mediated autoimmunity and T-cell-mediated immunity that are also responsible for a small, but significant, number of cases of epilepsy. Intravenous immunoglobulin therapy have been used to treat autoimmune diseases since last two decades and many new…