In clinicial practice, these enzymes are used widely alone or with NSAIDs for anti-inflammatory activities. Literature review indicates they only increase penetration of anti-inflammatory medications and antibiotics. They don't have anti-inflammatory action.
I have come across a paper which showed their anti-inflammatory activities which is comparable to diclofenac, naproxen, aspirin etc. What is your clinical experience with these enzymes ? Are they of any worth or just increase burden on patient's pocket?
