The impact of epilepsy is not only limited to the actual seizures but also inclusive of the effects of antiepileptic drugs (AEDs) as well as the psychosocial, psychiatric, cognitive and medical comorbidities associated with the seizure disorder. About 15 new AEDs have been added to treat the epilepsy in last two decades. Thus, this article highlights the mechanism of action of some AEDs with respect to their efficacy.
Epilepsy is the condition of recurrent spontaneous seizures happens due to aberrant electrical activity within the brain. Status epilepticus, stroke, brain tumors, prolonged febrile seizures, encephalitis, genetic malformations, and traumatic brain injury (TBI) are common conditions for development of pileptogenesis. Mechanism of seizure formation: Hyper-excitability of a neuron: Neuronal impulses are carried by action potential mediated by influx of sodium ion (positive)…
