Synopsis A recent clinical study demonstrates that significant correlation exist between adiponectin/leptin ratio (ALR) and insulin sensitivity, serum triglycerides, total cholesterol, LDL and HDL cholesterol levels in nondiabetic HIV infected males undergoing antiretroviral therapy (ART) . This week's ' MED FACT ' discusses a clinical trial from Endocrine Research, “ Association of adiponectin/leptin ratio with carbohydrate and lipid metabolism parameters in HIV-infected patients during antiretroviral therapy ”. 2018.

Authors : Tiliscan C; Arama V; Mihailescu R; Munteanu D; Iacob DG; Popescu C; Catana R; Negru A; Lobodan A; Arama SS. Key Takeaways Adiponectin and leptin play an important, but gender specific roles in the pathogenesis of lipid and glucose metabolism in HIV infected patients undergoing antiretroviral therapy. Objective Study Type Participants To study the relationship…