PRP vs Silicone for Scar Management Scar management remains a clinical challenge, with conventional silicone-based therapies offering variable outcomes. This randomized comparative study evaluated the efficacy of platelet-rich plasma (PRP) versus silicone-based products in 34 patients with post-surgical and post-traumatic scars over a 5-month follow-up. Patients received either intralesional PRP injections at 0, 1, and 3 months or continuous silicone gel/sheet application. PRP demonstrated significantly superior outcomes , with marked reductions in Patient and Observer Scar Assessment Scale (POSAS) scores across all time points (observer POSAS: 12.47 vs.
21.00 at 5 months, p<0.001; patient POSAS: 19.88 vs. 27.76, p<0.001). Improvement was evident as early as day 7 and sustained through 5 months. Patient satisfaction was also significantly higher in the PRP group (p<0.001), with no…
