A 2025 Frontiers in Endocrinology study compared fine-needle aspiration (FNA) and core-needle biopsy (CNB) for atypia of undetermined significance (AUS) thyroid lesions. CNB significantly improved malignancy detection and refined the diagnosis of NIFTP (noninvasive follicular thyroid neoplasm), marking it as the preferred diagnostic method in indeterminate thyroid cases. To read more; Click here ##Reference## Kim Y, et al. Malignancy risk in AUS thyroid lesions: comparison between FNA and CNB with implications for NIFTP diagnosis.
Front Endocrinol. 2025;16. https://doi.org/10.3389/fendo.2025.1692071.## Which finding supports CNB over FNA for AUS thyroid lesions? a) Improved malignant differentiation b) Simpler technique c) Lower procedural cost d) Reduced sampling volume
