Bleeding disorders may manifest as easy bruising, as serious spontaneous or excessive post-traumatic haemorrhage. Vascular disorders: Abnormal vessel walls can result in excessive bleeding including GI blood loss. Routine laboratory tests for haemostasis are normal. Platelet Defects: Thrombocytopenia is the most common platelet disorder and may occur as a bone marrow failure or another cause of pancytopenia. Platelet transfusion is given in severe bleeding.
Another cause is idiopathic thrombocytopenic purpura which can lead to falling in platelets. This requires treatment with steroids initially. Congenital disorders of coagulation: Haemophilia A and B are the most common inherited disorders of coagulation but are rare. Clinical features: At birth, all patients are healthy, though bleeding from cord and cephalo- haematoma may occur. During childhood, bleeding may occur in joints and…
