The guideline " Germline Testing in Patients with Breast Cancer: ASCO–Society of Surgical Oncology " provides recommendations for genetic testing in breast cancer patients. It is a comprehensive resource for medical professionals managing breast cancer patients, guiding them on when and how to conduct germline testing. The guideline includes the following key points: Testing recommendations: The guideline recommends BRCA1/2 mutation testing for all newly diagnosed breast cancer patients under 65 and selectively for those over 65 based on personal, family history, or treatment eligibility.
Additionally, it suggests considering testing for other high-penetrance cancer genes for patients with supportive family histories. Counseling and consent: It emphasizes the importance of providing patients with adequate pre-test information for informed consent. Patients with identified pathogenic…
