Several medications have genotoxic characteristics. As a result, healthcare workers may be exposed to these effects in various contexts, including dose preparation and delivery. There are currently no quantitative risk assessment models to predict the cancer risk of health workers exposed to genotoxic agents.
Based on the threshold of toxicological concern (TTC) idea, researchers created a quantitative risk assessment model to quantify the cancer risk of occupational exposure to genotoxic medicines in healthcare settings. This model was developed to assess the cancer risk of health professionals in modern healthcare facilities due to the handling of genotoxic medications. Method The TCC idea was developed by the International Council for Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) to ensure patient safety during long-term medication…
