Synopsis Pancreatic ductal adenocarcinoma (PDAC) has become one of the leading causes of cancer-related deaths. The present study aimed to compare the clinical utility of tumor monitoring in patients with metastatic PDAC using paired exoDNA and ctDNA to determine their prognostication and therapeutic stratification. This week’s “MED FACT” discusses a clinical trial from Gastroenterology, “Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer”. Authors: Bernard, Vincent, et al.
Key Takeaways Circulating Nucleic Acids Are Associated With both predictive and prognostic information of Patients With Pancreatic Cancer. Objective: To assess the clinical utility of circulating tumor cell DNA (ctDNA) and exosome DNA (exoDNA) in pancreatic cancer. Study Type: Prospective cohort Trial Participants: 194 What Was The Need For This Study? Pancreatic ductal…
