In what promises to be a breakthrough towards diabetes type 1 treatment and healing, scientists have found a possible solution with the replacement of destroyed beta-cells in patients with freshly produced cells that secrete insulin. Methods using adult and stem cells to induce this transformation have been tried for years, leading to an understanding of molecular mechanisms involved in beta cells development, yet the compound capable of doing this was missing. Coordinated by researcher, have found a lead in their research study (published in the Journal Cell), which shows that artemisinins work.
Researcher summarizes with this study, we could show that artemisinins change the epigenetic program of glucagon-producing alpha cells and induce profound alterations of their biochemical function. Beta and Alpha cells form together with at least three other cell types which are highly…
