Universally doctors are aware of occurrence of fever which is caused due to drugs. Some drugs may induce fever in some patients, however reliable data is still not available. This article aims to discuss etiology and management of fever which may be due to adverse drug reaction or which can be due to some other reasons.

Recognition of drug fever requires due attention as it has critical clinical importance. Failure to recognize the etiologic relationship between a drug and fever may have undesired consequences that may include extra testing, unnecessary therapy, and longer hospital stays. In general terms “a disorder characterized by fever coinciding with administration of a drug and disappearing after the discontinuation of the drug, when no other cause for the fever is evident after a careful physical examination and laboratory investigation” is considered as the most accepted…