A new monoclonal antibody called dupilumab is approved by FDA, U. S. for the treatment of atopic dermatitis (popularly known as eczema) which a ffect both children and adults. Atopic dermatitis is a type of chronic eczematous skin disease. The disease may genetically determined or elevated by environmental factors.
In the disease, dry, scaly, itchy patches develop in a characteristic distribution. Treatment of atopic dermatitis is centered around rehydrating the skin with emollients like petroleum jelly and the cautious use of topical steroids to reduce inflammation and itching. Use of oral antihistamine is also implicated in treatmentSince secondary infections can aggravate the rash, topical or oral antibiotics may also be occasionally indicated. A new monoclonal antibody-based treatment called dupilumab is approved in treating atopic dermatitis. Dupilumab is a fully human monoclonal…