The influence of antithyroid drugs (ATDs) on the therapeutic efficacy of radioactive iodine in hyperthyroidism is still unclear. This publication evaluates the effects of ATD discontinuation on the therapeutic efficacy of radioactive iodine in hyperthyroidism patients with long-term ATD treatment. Graves’ disease (GD) is the most common cause of hyperthyroidism. The treatment modalities for GD include ATDs, radioactive iodine, and thyroidectomy.
In this publication, the authors evaluated the effect of ATD discontinuation to the therapeutic efficacy of 131I in hyperthyroidism patients with long-term ATD treatment and defined the optimal time interval between ATD discontinuation and initiation of radioactive iodine therapy. In a retrospective controlled study conducted in 39 patients (8 men, 31 women), the patients were divided into 3 groups. The first group consisted of 14 patients who…
