Join us for Episode 2 of the podcast series, From Immunity to Protection: Expert Conversations on Pneumococcal Vaccination, where we delve into the critical scientific considerations that shape evidence-based pneumococcal vaccination. This episode explores why evaluating a pneumococcal conjugate vaccine requires more than simply comparing the number of serotypes it contains.
Through an evidence-based discussion, clinicians will gain insights into serotype epidemiology, serotype replacement, cross-protection, and the importance of local disease surveillance when assessing vaccine performance and informing vaccination strategies. 1 The discussion further explains the immunological principles underlying pneumococcal vaccine evaluation, including immunogenicity, immunobridging, IgG antibody responses, opsonophagocytic activity (OPA), correlates of protection, booster responses, and the…
