Sepsis is caused by an irregular host response to infection, leading to organ dysfunction. Septic shock is a part of sepsis with predominant abnormalities of the circulatory system and cellular metabolism. Sepsis is a life-threatening condition, while septic shock presents with increased mortality. 1  According to a global study, an estimated 48.9 million sepsis cases and 11.0 million sepsis-related deaths were recorded worldwide in 2017. 2 Early diagnosis and timely treatment are essential for patients with sepsis and septic shock.

Evans L. et al. have published guidelines in the journal Intensive Care Medicine for managing sepsis and septic shock in adult patients. 3 The guidelines are based on previous studies, the cost-effectiveness of the treatment, and the availability of advanced clinical equipment. 3 The recommendations from the guidelines can be categorized into the following…