Mrs X 32 yrs, managerial cadre, BMI 30, ML 1yr. Anxious to conceive. She had irregular periods and excess hair growth on face and body. Acanthosis nigricans was noticed, all the basic investigations were within normal limits. Transvaginal ultrasonography showed a pattern of polycystic ovaries. The patient was counselled regarding lifestyle modification and started on.
Metformin 500mg tid. After reducing 2 kg wt in 2 months, started on Letrozole from 3rd to 5th day. Duphaston 10mg from 16th to 25th day followed with the follicular study. A patient conceived in 3rd cycle. Inference. In obese PCOS letrozole will have better results after starting diet and exercise.
