Formulating liquid salts of drugs can be new safe and efficient way of topical delivery of drugs responsible for skin toxicity. The team of academicians from California, USA has formulated a liquid salt that can be delivered through skin with reduced toxicity. Skin toxicity remains a big hurdle in the drug design and use of new topical formulations. Due to the chemical nature of many formulations they need to be dissolved in organic solvents which are toxic to the skin. In addition, various compounds also show dose-dependent toxicity to the skin.
Propranolol is one such compound which shows skin toxicity. The scientists from University of California at Santa Barbara demonstrated novel formulation of propranolol as a liquid salt. This enables its delivery though skin with reduced toxicity. The team shielded positively charged propranolol with a counter species. This shielding reduced the…
