Key Takeaways Three years of testosterone supplementation did not improve the aerobic capacity of older men as seen from the VO 2 peak. However, a significant decline in VO 2 peak was observed for men in the placebo group. Objective: To understand the effect of long-term testosterone supplements on aerobic capacity in healthy older men with low testosterone Study Type: Double-blind, randomized, placebo-controlled, parallel-group trial Participants: 129 Synopsis Increase in age of men has been associated with a decline in the serum testosterone levels and hence associated changes in lean body mass and muscle strength.

Although testosterone supplementation and its effect on the physical strength have been studied, very few studies have focused on the long-term effects of testosterone supplementation on aerobic capacity of older men. The aim of this study was to evaluate these effects and…