Solve exciting clinical cases specific to your field of interest via Docplexus’ clinical case challenge. In this ‘Pharmacology Case Challenge’ join your fellow doctors to discuss and answer an interesting quiz. History A 23-year-old male had a renal biopsy four years ago that revealed a diffuse proliferative glomerulonephritis with no crescents. 30% of his glomeruli were obsolescent, and there was mild to moderate interstitial fibrosis.
The electron microscopy detected electron dense deposits within the mesangium and a diagnosis of IgA nephropathy was made. The patient has been treated with angiotensin receptor blocker (ARB) and his blood pressure at that time was in between 120-125/70 mm Hg. During this period, his serum creatinine transiently increased from 0.9 mg/dl to 2.0 mg/dl, each occurring at the time of synpharyngitic flares of his disease. One year ago, he had another…