The recent research on chronic degenerative diseases (CDD), such as obesity, diabetes, neurodegeneration, atherosclerosis, autoimmune diseases, cancer and aging itself, has shown that Venous and Lymphatic Diseases (VLD) may play an important role in their development, de facto pushing phlebology and especially lymphology under a spotlight in biomedical research. Veins and especially lymphatics have a determinant role in the tissue homeodynamics/clearance, and similarly, it is known that tissue degeneration accompanies all CDD (and VLD); consequently, venous and lymphatic morpho-dynamic abnormalities may represent important components in the complex puzzle of CDD pathophysiology.
The clinical manifestations of VLD also reflect several other epigenetics-related cocausal factors (such as obesity, erroneous lifestyle, drug intake, postural changes, musculovascular pump dysfunction, etc.)…
