Blindness is a one of the major health concern that has a powerful impact on the affected individuals as well as on the family members and also associated with social economic consequences. Efficient ocular drug delivery remains a challenge for pharmaceutical scientists. This article gives you an insight on some of the nanotechnology-based drug approaches to explore the frontiers of ocular drug delivery. An eye is a unique organ, functioning physiologically and contains several widely varied structures.

The physiologic factors, which can affect a drug’s ocular bioavailability include protein binding, drug metabolism and lacrimal drainage. In addition to physiologic factors, other factors as like physicochemical characteristics of the drug substance, and product formulation is also important. Challenges in ophthalmic drug delivery systems The anatomy, physiology, and biochemistry of the…