Background and study aims: Per-oral endoscopic myotomy (POEM) has emerged as an efficacious treatment modality for the management of achalasia cardia (AC) and non-achalasia spastic esophageal motility disorders. Initial results are encouraging. We analyzed the safety and efficacyof POEM in a large cohort of patients with AC. Patients and methods: The data from patients who under went POEM (from January 2013 to June 2016) was prospectively collected and analyze d.
Clinical success was defined as Eckardt score ≤ 3 after POEM procedure. Objective parameters including high-resolution manometry (HRM)and timed barium swallow (TBS) were analyzed and com-pared before and after the procedure. Gastroesophageal reflux was analyzed using 24-hour pH impedance study and esophagogastro-duodenoscopy. Results: A total of 408 patients (mean age 40 years, range 4 – 77 years) under went POEM during the…
