Pain management is carried out using several drugs and their combinations. The non-opioid drugs and compound analgesics act by inhibiting cyclooxygenase-2 that plays a role in prostaglandin synthesis while opioid drugs target the receptors present on pre- and post-synaptic membrane. Clinical evidence shows that NSAIDs are used more often than other drugs. Pain may be a result of inflammation caused by tissue damage, pathogens, chemical agent or nerve damage. There are plenty of drugs used in the treatment of pain available in India.
These include Non-steroidal Anti-Inflammatory Drugs (NSAIDs), Aspirin, Paracetamol and Opioid medication. What causes pain? Tissue damage causes release of prostaglandins which cause inflammation, pain and pyrexia. Most of the drugs act by preventing prostaglandin production which relieves pain but also causes imbalance in the proper functioning of…
