Adrenaline: Presentation:- Available as clear solution for injection containing 1mg/ml of Adrenaline hydrochloride. It also comes as aerosol spray delivering 280 micrograms metered dose of Adrenaline acid tartare. Chemical origin:- A Catecholamine t1/2 is 2 two Minutes Dose:- 1 Dose regimen for pressure support (a) 1--2 micrograms/minute predominantly activates beta2 receptors leading to vascular and bronchial smooth muscle relaxation ( b)2--10 micrograms/min(25--120 ng/kg/min) bete1&2 action.Heart rate, contractility and AV node conduction increased.
(C) >10microgrames ( >100ng/kg/min) marked alpha stimulation & generalised vasoconstrictions 2. Dose for CPRI 1mg(.02 mg/ kg ) iv Adrenaline stat is given for asystole ,vf and EMD . In situations where iv access is not available Adrenaline dose is tripled and diluted in 10 ml saline, to be given via endotracheal tube or intra Osseous route…
