Multiple proton pump inhibitors are available nowadays. Among them are: Pantoprazole, Omeprazole, Lansoprazole, Dexlansoprazole, Ilaprazole, Esomeprazole, Rabeprazole. Indications of Proton Pump Inhibitors: Dyspepsia Peptic Ulcer Disease As a Part of H. Pylori Eradication Therapy GERD and NERD Barrett’s Esophagus Eosinophilic esophagitis Stress gastritis and ulcer prevention in critical care unit Gastrinomas and other conditions that cause hypersecretion of acid including ZES.
CONCERNS ABOUT LONG TERM PPIs USAGE: Development of chronic kidney disease. Development of mineral, vitamin and trace element deficiency. Long-term usage is associated with the development of dementia, bone fractures and myocardial infarction, gastrointestinal malignancies and secondary infections. Clinical practice update/ best practice advice: Patient with GERD and acid-related complications should take a PPI…
