Amygdala, structure activated by stress in the brain, causes the incresed production of inflammatory WBCs from bone marrow which causes atherosclerosis of aorta and cardiovascular events.This is a unique thought which needs more evidence to the bed side. But it opens our eyes towards assessment of patient's psychological stress or other psychiatric comorbidities to improve the risk of vascular events, patients.

This explains the association of loss of loved ones leading to heart attacks and stroke. Are you relieved of having a genuine answer for patient's queries?