Tab Sitagliptin acts synergistically with Semaglutide injection , especially in obese diabetic patients. Semaglutide directly mimics the GLP-1 hormone (approximately 94% structural similarity ) to activate GLP-1 receptors for a prolonged period because it resists enzymatic degradation. Sitagliptin blocks the DPP-4 enzyme , thereby preserving the body's natural GLP-1.
Together, this may act synergistically with Semaglutide, potentially providing better results than Semaglutide alone. Please try and share your experiences.