Tuberculosis remains one of the major communicable diseases. There are number of diagnostic tests available for the diagnosis of tuberculosis but conventional microscopy has low sensitivity and culture although gold standard, takes longer time for positivity. Aim: To evaluate the sensitivity, specificity, PPv & NPV of Nucleic acid amplification assay (GeneXpert) using respiratory samples in patients with suspected pulmonary tuberculosis and compare with AFB smear microscopy and AFB culture. Materials and Methods: 89 patients from April 2015 to July 2017 for ZN stain, culture and GeneXpert (MTB/Rif assay) were studied.
The sensitivity, specificity, PPV and NPV of GeneXpert and ZN microscopy were calculated using Liquid culture of Mycobacterium tuberculosis as gold standard. Results: A total of 89 patient samples were evaluated in final analysis. Of these, 16 samples were positive by all…
