A 72-year-old man presented with a spontaneous fracture of his left wrist. Physical examination suggested an additional fracture of his right wrist. Conventional radiograph showed extensive osteolytic lesions with fractures of both distal ulnae (figure A and B). He reported no recent weight loss, night sweats, prostatic problems, or deteriorating performance status.

There was no lymphadenopathy on physical examination. Positron emission tomography showed no primary tumour in the abdomen or thorax and no other skeletal lesions, nor was there any suspicion of prostate carcinoma. What can be the cause of these isolated osteolytic lesions in this 72-year-old man with no suspicion of prostate carcinoma? *This case is from Docplexus Editorial Team for educative purpose only Source: The Lancet Click here for correct answer!