Any clinical feature presented outside on the body is the manifestation of the biochemical change inside the body. The reasons for the internal changes can be many. But if a viral infection is responsible for it, then the differences in the amount of virus (viral load) entered into the body matters a lot. The subsequent mounting of immune responses depends on it.

Any clinical manifestation is the cumulative effect of both the viral load and mounted immune response. The human body maintains its internal organization by means of membranes, sheaths, and other structures that separate compartments. These cavities contain and protect delicate internal organs, and allows for significant changes in the size and shape of the organs as they perform their functions. The lungs, heart, stomach, and intestines, for example, can expand and contract without distorting other tissues or disrupting the…