Skin biopsy is a vital diagnostic process performed frequently in dermatology practice. Biopsies can be classified as incisional, in which only a part of a lesion is sampled, or excisional in which the physician removes all of the visible parts of a lesion.
An effort is made to provide the pathologist with as much tissue as clinically reasonable, from a location with the highest possibility of diagnostic yield, while causing as little disfigurement and compromise of function to the patient as possible.