A 24-year-old trainee accountant feels abnormally tired. Previous medical knowledge: Limited, apart from her visit several months prior contraception after a termination of pregnancy. At the start of the consultation, she sits down and describes how she has been feeling abnormally tired for the last few weeks. Q1: What are the diagnostic possibilities? General consultation The physician decides to know more and lets her talk freely for a few minutes, listening closely and observing her body language.

She points that she has been finding it difficult to get to sleep because work problems have been going round and round in her mind and even when she eventually drops off she has bad dreams. At work her concentration is poor and she has been recently working 10 h every day to complete everything. She says she feels she is useless, as she is always the last one to leave the office. Yesterday…